I have noticed that too, Annie, when there is less than a quarter left in the canister. However, I have not connected it with the idea that the fuel has become weaker. The glass matting-like stuff in the alcohol canister appears to have a strong wick-effect and thus spreads the fuel around in this material. As the canisters is nearing empty, the wick material will naturally turn drier and the stove will burn with less intensity.
I might be wrong, but this is my conclusion about it.
It takes a real fool to produce a run-away alcohol fire in that stove. Still, I have a fire blanket at hand, in addition to my 5-litre cans of water.
Arne
PS: In the specs for the Origo, it says that a canister takes 1.2l alcohol. With my 1l-bottles, it is natural to only fill with one litre. This lets me sail Ingeborg on her ear without fearing fuel spill, even if my stove is not gimballed.