In most boats, putting the mast on the centre-line of the boat interferes with the accommodation somewhat, dividing the V-berth or especially, sitting in the middle of the access to same.  More of an issue with a Split Rig or Aero Rig

By offsetting the mast to one side, more space could be created to one side of the passageway for getting forward.

Has anyone ever done this?

How much could one offset the mast before it might start having a negative effect in terms of having to use too much rudder to keep the boat driving forward in a straight line?

More curious than anything else, but thinking towards If I get a larger boat in the future.

Dave D.